Associate Researcher - Integrated Resources, Inc ( IRI ) : Job Details

Responsibilities -

• This position offers the opportunity to impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment.
• Independently, develop, optimize, and proactively troubleshoot cellular screening assays.
• Responsible for generating, processing, interpreting, and presenting data in cross functional team meetings.
• Proactively employ cell and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action.
• Independently design, execute and document experiments to evaluate target dependency, off target liabilities, phenotypic responses and identifying resistance mechanisms.
• Regularly share and present data with team members.

Required Skills -

• MS/BS in oncology, cellular biology, molecular biology, or related discipline with 1+ years of industry or relevant research experience is required.

Preferred Skills -

• Experience in developing and optimizing cell-based assays in multiple platforms (for example CTG, HTRF, AlphaLISA, FC, Jess-WB, NanoBret, Nanostring).
• Experience with different molecular and cellular biology techniques (such as Western Blot).
• Experience with genome editing (CRISPR or si/shRNA) for engineering cell line models is a plus.
• Familiar with tumor models and establishing PK/PD/efficacy relationships and delivering PD readouts by western blots for in vivo tumor models.
• Experience with standard software analytical tools, xlsx, Prism, or other synergy software.
• Strong oral and written communication skills, as well as excellent documentation and organizational skills.
• A team player, who listens effectively, invites response and discussion.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism.