Process Development Engineer I, Purification Development - Regeneron Pharmaceuticals : Job Details

Regenerons Late-Stage Purification Development team within PMPD (Preclinical Manufacturing and Process Development) is seeking an energetic Process Development Engineer I. In this role, you will be responsible for the development, characterization, and transfer of various membrane-based downstream purification processes, including viral retentive filtration, ultrafiltration/diafiltration, and sterile filtration for recombinant proteins, using Quality by Design principles.

• Reads and interprets published literature, designs and completes experiments at both bench and pilot-scale
• Analyzes data, draws conclusions from results, and proposes next steps
• Documents results in laboratory notebook and reports
• Communicates findings to functional area and department leadership
• Acts as purification development subject matter expert during manufacturing process transfer to ensure successful completion of GMP batches
• Works multi-functionally with the process development team to enable a robust, cohesive manufacturing process
• Supports technology development and improvement activities potentially including but not limited to improving bench-scale process models, developing workflows for compilation and analysis of historical data, investigating new raw materials, equipment, and/or techniques for purification, concentration, and formulation of biologics using membranes.
• Trains peers and directly or indirectly manages, mentors, and assists co-op students and interns in conducting experiments, analyzing data, and documenting results.
• Contributes to lab equipment maintenance and general lab safety to help create a safe, effective, and efficient working environment

• Have a solid understanding of chemical engineering fundamentals (mass and energy balance, thermodynamics, mass transfer, and transport phenomenon) and practical experience in purifying monoclonal antibodies or other biopharmaceuticals
• Enjoy spending ~50-70% of time performing lab work at both bench and pilot-scale
• Thrive in a team-based, collaborative environment
• Are well organized and able to manage multiple projects efficiently
• Are an effective communicator within all levels of an organization
• Are scientifically curious, creative, and have a problem-solver and growth mindset

This role requires a Bachelors and/ or Masters degree in either Chemical Engineering, Biochemical Engineeringor a related field with 3-5/1-2 years of recombinant protein purification experience, including some but not limited to depth filtration, disc stack centrifugation, column chromatography, virus retentive filtration, ultrafiltration/diafiltration, buffer preparation. A strong fundamental understanding of various protein purification techniques and experience with Akta chromatography systems, HPLC, UPLC, Empower, Unicorn, JMP, LIMS, and PI Historian is a plus.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)