5 Month Contract (May extend or convert to permanent)
$40/hour - $60/hour W2 (Depending on previous experience)
Position Details:
- Independently, develop, optimize, and proactively troubleshoot cellular screening assays.
- Responsible for generating, processing, interpreting, and presenting data in cross functional team meetings
- Proactively employ cell and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action.
- Independently design, execute and document experiments to evaluate target dependency, off target liabilities, phenotypic responses and identifying resistance mechanisms.
- Regularly share and present data with team members.
Position Requirements:
- MS in oncology, molecular biology, cell biology, or related discipline with 2+ years of industry experience OR BS in oncology, molecular biology, cell biology, or related discipline with 4+ years of industry experience
- Experience in developing and optimizing cell-based assays in multiple platforms (for example CTG, HTRF, AlphaLISA , FC, Jess-WB, NanoBret, Nanostring).
- Experience with different molecular and cellular biology techniques (such as Western Blot).
- Experience with genome editing (CRISPR or si/shRNA) for engineering cell line models is a plus.
- Familiar with tumor models and establishing PK/PD/efficacy relationships and delivering PD readouts by western blots for in vivo tumor models.
- Experience with standard software analytical tools, xlsx, Prism, or other synergy software.
- Strong oral and written communication skills, as well as excellent documentation and organizational skills.
- A team player, who listens effectively, invites response and discussion.