Scientist II - AbbVie : Job Details

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

AbbVie's Genomics Research Center (GRC) is a center of excellence for genetics and genomics that supports both Discovery and Development. The GRC goal is to develop world class genetics and genomics research focused on finding the right therapeutic targets and helping AbbVie scientists better understand not only human disease biology but also the behavior and response to our drugs in clinical trials across all therapeutic areas.

The Functional Genomics team within the GRC provides expertise in genome editing and CRISPR technology to discover and validate novel drug targets for AbbVie's therapeutic pipelines in Immunology, Oncology, Ophthalmology, Aesthetics and Neuroscience. We utilize cutting-edge genomic techniques to transform human genetics data into drug targets, to identify pathogenetic mechanisms, and develop new biomedical technologies. We apply high-throughput functional genomic screening approaches to in vitro and in vivo preclinical models with diverse molecular and phenotypic readouts. We perform hypothesis-driven research for target validation and execute mechanistic studies utilizing a variety of genomics tools.

We have an exciting opportunity for a talented and highly motivated scientist to join our collaborative team of geneticists, molecular and cellular biologists, and computational biologists to support functional genomics and genetic medicine research. Applicants should have broad laboratory research experience using cell and molecular biology techniques. Open communication and curiosity are essential. The candidate is expected to operate in a fast-paced, multi-disciplinary setting and must be able to execute multiple research projects in parallel.

Key Responsibilities:

* Perform CRISPR and functional genomics research.

* Generate, modify, and utilize lentivirus and adeno-associated virus (AAV).

* Participate in cross-functional target identification and validation projects to support drug discovery efforts across multiple therapeutic areas.

* Develop cell-based functional assays using cell lines.

* Perform Molecular Biology techniques such as PCR and NGS library generation.

* Collaborate extensively with scientists across diverse functional and therapeutic areas in a matrixed research environment

* Communicate and present project designs and results clearly, both to individual stakeholders and in group settings

Qualifications

* B.S. or M.S. in Molecular biology, Cell biology, or in a related discipline with expertise in molecular genetics, with typically 5+ (BS) or 2+ (MS) years of job-related experience.

* A background and working knowledge in the delivery of genetic medicines is required.

* Experience in molecular biology techniques, such as PCR, CRISPR, high throughput screening, and viral particle synthesis, is required.

* Experience in in vitro cell culture and development of cell-based assays is required.

* Ability to learn new skills and apply them in a fast-paced research environment is a must.

* Creativity, problem-solving, and attention to details are required.

* Strong communication and collaboration skills are essential. Ability to work independently as well as in a team is a must.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

* The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

* We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

* This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status